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Little clicked for the Bills' quarterback in a tough contest on Thursday evening against the Texans.

And still he nearly managed to driving the Bills to a victory before an interception in the last moments sealed their fate in a 23-19 defeat.

Allen endured consecutive tackles for loss on the team's final possession, resulting in a fourth-and-27, but Buffalo (7-4) gained 44 yards on a quick throw from Allen to a receiver, who tossed a backward pass to Khalil Shakir.

Following a pre-snap infraction created a fourth down situation for Buffalo, Calen Bullock picked off the quarterback's pass at the Houston 9 with under half a minute remaining.

We possessed a opportunity to come out on top there at the conclusion,” Josh Allen stated. “Our team performed a solid job of hanging tough and our defensive unit bailed us out a few instances. We must figure it out, and we didn’t.”

It was tough for the signal-caller to get anything going on a evening he was brought down a personal-worst on eight occasions and pressured four additional instances. The QB passed for 253 passing yards with two interceptions and no touchdowns after accounting for six TDs in a win over the Buccaneers the previous week.

Whenever they hit our QB 12 times, that's unacceptable,” Bills coach Sean McDermott said. “I don’t like that statistic at all. It is not a healthy way to play and it isn't a good way to preserve our field general healthy for the rest of the season. We’ve got to improve our performance.”

Allen was slow to rise after a sack in the opening two quarters. He said he was fine and that his left shoulder “lost some feeling” after he landed on it in an awkward manner. He was questioned about being contacted so frequently on Thursday.

It's unpleasant,” he remarked. “I ran into a couple personally. I’ve got to be better at throwing the ball away. Too many times, I found myself losing ground.”

Allen lost 70 yards on the eight quarterback takedowns. Will Anderson Jr. had 2.5 sacks to top the Houston defense. His second one occurred when he almost took Allen down near the line of scrimmage, but he wriggled away and Anderson rose and pursued him downfield to drop him for an 18-yard deficit to result in a punt in the third quarter.

Buffalo competed for a second consecutive matchup without receiver Keon Coleman after he was once more a healthy scratch after he was late to a squad gathering before their last game. He was previously benched for the opening drive of a defeat to New England in Week 5 after additionally being late for a team session.

No change. We are taking it one day at a time,” McDermott said. “I thought he had a improved week, but we are handling it one day at a time. It wasn’t that it wasn’t thought about, but we opted for the guys that provide the optimal opportunity.”

Khalil Shakir led the Bills with eight catches for 110 receiving yards and James Cook had 116 yards and a touchdown.

The quarterback was frustrated that the team were unable to make plays in crucial moments.

In the end, we must execute, and we didn’t succeed of that this evening,” he concluded. “No matter the situation and any condition, we need to find a way, and we came up short.”